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AAS like testosterone are used in androgen replacement therapy , a form of hormone alternative therapy , and for different indications. For men , a testosterone supplement of the 5,000 mg dose was shown to result in a slight increase in lean muscle weight, and lower levels of the sex hormone binding globulin as measured by the free testosterone concentration [ 19 ]. It also has beneficial hormonal effects through its effects on the adrenal glands [ 20 – 22 ]. In terms of the anti-aging effects of testosterone , a small placebo effect was reported in a review of a study of male androgenic blockers published in 2011 [ 23 ]. In this study, no anti-aging effects were observed in healthy male subjects as compared to a testosterone placebo group. Similarly , few studies had already reported significant anti-aging effects in healthy male subjects and older women with testosterone replacement therapy [ 18 – 21 ]. As the beneficial effects of testosterone, on the cardiovascular endpoints, are not the norm, it is not surprising that anti-aging actions of testosterone are not as well documented nor as well known as other steroids on the vascular system . A possible reason for the difference could be that the beneficial cardiovascular effects of testosterone might vary from individual to individual and may not be the result of specific effects on vascular health. Since testosterone has been shown to inhibit the oxidative damage by reducing arterial endothelial lipids, it may have anti-aging effects. Moreover, testosterone’s estrogen activity is associated with the reduction in the level of the circulating estrogen receptor in the plasma of men [ 24 ]. Therefore, in men testosterone might not be useful for any anti-aging effect and might instead be associated with lower levels of estrogen in the blood [ 25 ]. Another possible reason for the heterogeneity between the anti-aging actions of testosterone may also be its low levels of bioavailable testosterone . Since in healthy human males testosterone levels are high even after the administration of a low dose of testosterone, and with the use of testosterone replacement therapy , it is important to take into account the lower levels of bioavailable testosterone . In fact, the levels of bioavailable testosterone in men were low when testosterone was tested in a study of low-dosage testosterone replacement therapy [ 28 ], thus not being able to directly influence on some of the anti-aging effects of testosterone. In addition to the potential problems due to different doses of testosterone , there are some difficulties related to the bioavailability and bioactivity of testosterone in serum . The bioavailability of testosterone is a characteristic of the total serum testosterone concentration. In healthy subjects, serum concentrations are generally higher than the bioavailability of the testosterone. Because high concentrations of bioavailable testosterone have a higher bioavailability , a higher
Nandrolone npp deca durabolin polvo esteroide bruto paypal bitcoin aceptado. Grupo operacional – vespa velutina forum – member profile > profile page. User: ciclo de deca durabolin, ciclo de decadurabolin y sustanon,. — deca-durabolin funciona perfectamente en un ciclo de aumento de volumen con dosis de hasta 600 mg/semana durante 12-16 semanas; o dosis de 400. — la durata di un ciclo deca varia da 8 a 14 settimane, poiché si tratta di una sostanza ad azione lenta. Tra gli effetti positivi che il corpo. Deca durabolin: 200mg settimana 1-12. Dianabol: 25mg al giorno settimana 1-6. Un altro perfetto steroide per il ciclo di carica del principiante è iniziato. 2016 — ciclo básico. Período: de 1 a 8 semanas
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